Casarano to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lecce and arrive at Messina Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Casarano to Messina train schedule: the first train leaves at 07:15, while the last ride is at 07:15. A Casarano to Messina train cost about 36.6 €. But how long is the train ride from Casarano to Messina? Your journey takes about 12 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Casarano to Messina and find low cost tickets starting from 41 €!