Cassino to Grottaglie trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cassino and arrive at Grottaglie every about 2 hours on average. If travelling with Trenitalia, you need to know the Cassino to Grottaglie train schedule: the first train leaves at 05:50, while the last ride is at 15:15. A Cassino to Grottaglie train cost about 46.7 €. But how long is the train ride from Cassino to Grottaglie? Your journey takes about 8 hours on average.