Castelvetrano to Perugia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Castelvetrano and arrive at Perugia every about 2 hours on average. If travelling with Trenitalia, you need to know the Castelvetrano to Perugia train schedule: the first train leaves at 07:01, while the last ride is at 19:32. A Castelvetrano to Perugia train cost about 96.35 €. But how long is the train ride from Castelvetrano to Perugia? Your journey takes about 18 hours on average.