Città di Castello to Mestre trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Venezia Mestre every about 1 hour on average. If travelling with ItaloTreno, you need to know the Città di Castello to Mestre train schedule: the first train leaves at 17:55, while the last ride is at 20:25. A Città di Castello to Mestre train cost about 35.0 €. But how long is the train ride from Città di Castello to Mestre? Your journey takes about 2 hours on average. ItaloTreno offers 2 direct trains between these two cities. There are also Trenitalia trains from Città di Castello to Mestre; you can compare ItaloTreno and Trenitalia with Wanderio, so that you find the best fare in a quick and simple way. A Città di Castello to Mestre train ticket with Trenitalia costs 25.90 € on average and you can find rides from 15:30 to 20:30. Thanks to ItaloTreno, Trenitalia offers, you can save on your trip from Città di Castello to Mestre and find low cost tickets starting from 19 €! When booking your train ticket a few weeks in advance though, you can find low cost trains from Città di Castello to Mestre with fares starting from 25.90€, saving up to 16%.