Comiso to Lecce trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Comiso and arrive at Lecce every about 12 hours on average. If travelling with Trenitalia, you need to know the Comiso to Lecce train schedule: the first train leaves at 18:22, while the last ride is at 18:22. A Comiso to Lecce train cost about 132.9 €. But how long is the train ride from Comiso to Lecce? Your journey takes about 19 hours on average.