Florence to Pisa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Pisa Centrale every 15 minutes on average. If travelling with Trenitalia, you need to know the Florence to Pisa train schedule: the first train leaves at 06:03, while the last ride is at 21:57. A Florence to Pisa train cost about 8.0 €. But how long is the train ride from Florence to Pisa? Your journey takes about 1 hour on average. Trenitalia offers 49 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Florence to Pisa and find low cost tickets starting from 8 €!