Mestre to Caserta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia Mestre and arrive at Napoli Centrale every 30 minutes on average. If travelling with Trenitalia, you need to know the Mestre to Caserta train schedule: the first train leaves at 06:54, while the last ride is at 16:54. A Mestre to Caserta train cost about 71.3 €. But how long is the train ride from Mestre to Caserta? Your journey takes about 6 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Mestre to Caserta and find low cost tickets starting from 39 €!