Milan to Misano Adriatico trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Misano Adriatico every 60 minutes on average. If travelling with Trenitalia, you need to know the Milan to Misano Adriatico train schedule: the first train leaves at 04:35, while the last ride is at 19:45. A Milan to Misano Adriatico train cost about 17.85 €. But how long is the train ride from Milan to Misano Adriatico? Your journey takes about 3 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Milan to Misano Adriatico and find low cost tickets starting from 16 €! If you need to travel this week, prices start from 17.85€ to a maximum price of 35.78€. When booking your train ticket a few weeks in advance though, you can find low cost trains from Milan to Misano Adriatico with fares starting from 17.85€, saving up to 29%.