Milazzo to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milazzo and arrive at Alessandria every about 2 hours on average. If travelling with Trenitalia, you need to know the Milazzo to Alessandria train schedule: the first train leaves at 15:55, while the last ride is at 23:47. A Milazzo to Alessandria train cost about 111.35 €. But how long is the train ride from Milazzo to Alessandria? Your journey takes about 17 hours on average.