Palermo to Iesi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Palermo Centrale and arrive at Jesi every about 2 hours on average. If travelling with Trenitalia, you need to know the Palermo to Iesi train schedule: the first train leaves at 18:30, while the last ride is at 21:10. A Palermo to Iesi train cost about 74.0 €. But how long is the train ride from Palermo to Iesi? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Palermo to Iesi and find low cost tickets starting from 96 €!