To get from Senigallia a Casarano by train you can catch one of the 11 trains that everyday travel between Senigallia and Lecce, the closest station to the city. For your trip from Senigallia to Lecce by train you can choose to leave from one of Senigallia main stations: Senigallia If travelling with Trenitalia, you need to know the Senigallia to Lecce train schedule: the first train leaves at 10:55, while the last ride is at 23:01. A Senigallia to Lecce train cost about 41.65 €. But how long is the train ride from Senigallia to Lecce? Your journey takes about 7 hours on average.