Syracuse to Anzio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siracusa and arrive at Villa Claudia every about 2 hours on average. If travelling with Trenitalia, you need to know the Syracuse to Anzio train schedule: the first train leaves at 19:10, while the last ride is at 21:45. A Syracuse to Anzio train cost about 52.6 €. But how long is the train ride from Syracuse to Anzio? Your journey takes about 14 hours on average.