Termoli to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Termoli and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Termoli to Messina train schedule: the first train leaves at 06:28, while the last ride is at 18:28. A Termoli to Messina train cost about 81.0 €. But how long is the train ride from Termoli to Messina? Your journey takes about 12 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Termoli to Messina and find low cost tickets starting from 54 €!