Trapani to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Trapani and arrive at Palermo Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Trapani to Palermo train schedule: the first train leaves at 09:38, while the last ride is at 18:30. A Trapani to Palermo train cost about 10.4 €. But how long is the train ride from Trapani to Palermo? Your journey takes about 4 hours on average. Trenitalia offers 2 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Trapani to Palermo and find low cost tickets starting from 11 €!