Varese to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Varese and arrive at Caltanissetta Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Varese to Caltanissetta train schedule: the first train leaves at 15:36, while the last ride is at 17:36. A Varese to Caltanissetta train cost about 203.3 €. But how long is the train ride from Varese to Caltanissetta? Your journey takes about 19 hours on average.