Vasto to Sienna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Porto di Vasto and arrive at Siena every about 2 hours on average. If travelling with Trenitalia, you need to know the Vasto to Sienna train schedule: the first train leaves at 08:36, while the last ride is at 16:15. A Vasto to Sienna train cost about 116.4 €. But how long is the train ride from Vasto to Sienna? Your journey takes about 9 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Vasto to Sienna and find low cost tickets starting from 51 €!