To get to Mesagne from Alessandria you can take a flight from Genoa Cristoforo Colombo Airport, which is the closest airport to Alessandria, and arrive at Brindisi – Salento Airport, the airport the best serves Mesagne. The average price for a Alessandria to Mesagne flight is 221€, but you can find low cost flights as well, with prices starting from 77€. Getting from Alessandria to Mesagne by flight takes about 1 hour on average; however, you need to consider the time to get to the airport and pass the security checks. You can count on 85 daily connections between Alessandria and Mesagne provided by Lufthansa, easyJet, and Air Italy. Brindisi – Salento Airport is the closest airport to Mesagne and is 25 kilometers away from the city center; you can get to Mesagne in 38 minutes thanks to airport shuttles from Brindisi – Salento Airport to Mesagne.