Acqui Terme to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Acqui Terme and arrive at Avola every about 3 hours on average. If travelling with Trenitalia, you need to know the Acqui Terme to Avola train schedule: the first train leaves at 13:34, while the last ride is at 20:49. A Acqui Terme to Avola train cost about 83.55 €. But how long is the train ride from Acqui Terme to Avola? Your journey takes about 22 hours on average.