Acqui Terme to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Acqui Terme and arrive at Enna every about 6 hours on average. If travelling with Trenitalia, you need to know the Acqui Terme to Enna train schedule: the first train leaves at 13:37, while the last ride is at 20:49. A Acqui Terme to Enna train cost about 186.9 €. But how long is the train ride from Acqui Terme to Enna? Your journey takes about 22 hours on average.