Acqui Terme to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Acqui Terme and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Acqui Terme to Palermo train schedule: the first train leaves at 09:42, while the last ride is at 20:49. A Acqui Terme to Palermo train cost about 117.75 €. But how long is the train ride from Acqui Terme to Palermo? Your journey takes about 19 hours on average.