Alessandria to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alessandria and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Alessandria to Alpignano train schedule: the first train leaves at 04:12, while the last ride is at 21:31. A Alessandria to Alpignano train cost about 8.7 €. But how long is the train ride from Alessandria to Alpignano? Your journey takes about 2 hours on average.