Alpignano to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alpignano and arrive at Niscemi every about 4 hours on average. If travelling with Trenitalia, you need to know the Alpignano to Niscemi train schedule: the first train leaves at 16:55, while the last ride is at 20:55. A Alpignano to Niscemi train cost about 179.95 €. But how long is the train ride from Alpignano to Niscemi? Your journey takes about 8 hours on average.