Alpignano to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alpignano and arrive at Siracusa every about 3 hours on average. If travelling with Trenitalia, you need to know the Alpignano to Syracuse train schedule: the first train leaves at 06:25, while the last ride is at 20:55. A Alpignano to Syracuse train cost about 71.75 €. But how long is the train ride from Alpignano to Syracuse? Your journey takes about 19 hours on average.