Anzio to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Villa Claudia and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Anzio to Alessandria train schedule: the first train leaves at 05:03, while the last ride is at 22:13. A Anzio to Alessandria train cost about 52.0 €. But how long is the train ride from Anzio to Alessandria? Your journey takes about 7 hours on average.