Asti to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Asti and arrive at Comiso every about 4 hours on average. If travelling with Trenitalia, you need to know the Asti to Comiso train schedule: the first train leaves at 16:54, while the last ride is at 22:36. A Asti to Comiso train cost about 86.0 €. But how long is the train ride from Asti to Comiso? Your journey takes about 7 hours on average.