Avezzano to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Avezzano and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Avezzano to Syracuse train schedule: the first train leaves at 06:54, while the last ride is at 19:07. A Avezzano to Syracuse train cost about 80.8 €. But how long is the train ride from Avezzano to Syracuse? Your journey takes about 15 hours on average.