Brindisi to San Severo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at S. Severo every about 1 hour on average. If travelling with Trenitalia, you need to know the Brindisi to San Severo train schedule: the first train leaves at 04:00, while the last ride is at 19:27. A Brindisi to San Severo train cost about 35.50 €. But how long is the train ride from Brindisi to San Severo? Your journey takes about 3 hours on average. Trenitalia offers 1 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Brindisi to San Severo and find low cost tickets starting from 28 €!