Caltanissetta to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caltanissetta Centrale and arrive at Messina Centrale every about 1 hour on average. If travelling with Trenitalia, you need to know the Caltanissetta to Messina train schedule: the first train leaves at 04:42, while the last ride is at 17:51. A Caltanissetta to Messina train cost about 11.0 €. But how long is the train ride from Caltanissetta to Messina? Your journey takes about 5 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Caltanissetta to Messina and find low cost tickets starting from 11 €!