Cantù to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Como S. Giovanni and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Cantù to Alessandria train schedule: the first train leaves at 07:13, while the last ride is at 19:13. A Cantù to Alessandria train cost about 11.9 €. But how long is the train ride from Cantù to Alessandria? Your journey takes about 3 hours on average.