Casa Santa to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Trapani and arrive at Ragusa every about 12 hours on average. If travelling with Trenitalia, you need to know the Casa Santa to Ragusa train schedule: the first train leaves at 05:43, while the last ride is at 05:43. A Casa Santa to Ragusa train cost about 21.4 €. But how long is the train ride from Casa Santa to Ragusa? Your journey takes about 13 hours on average.