Casalecchio di Reno to Brescia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casalecchio di Reno and arrive at Brescia every 60 minutes on average. If travelling with Trenitalia, you need to know the Casalecchio di Reno to Brescia train schedule: the first train leaves at 05:49, while the last ride is at 21:42. A Casalecchio di Reno to Brescia train cost about 14.85 €. But how long is the train ride from Casalecchio di Reno to Brescia? Your journey takes about 3 hours on average.