Casalecchio di Reno to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casalecchio di Reno and arrive at Milazzo every about 2 hours on average. If travelling with Trenitalia, you need to know the Casalecchio di Reno to Milazzo train schedule: the first train leaves at 08:14, while the last ride is at 21:14. A Casalecchio di Reno to Milazzo train cost about 102.3 €. But how long is the train ride from Casalecchio di Reno to Milazzo? Your journey takes about 15 hours on average.