Casalnuovo di Napoli to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casalnuovo di Napoli and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Casalnuovo di Napoli to Niscemi train schedule: the first train leaves at 08:56, while the last ride is at 08:56. A Casalnuovo di Napoli to Niscemi train cost about 62.95 €. But how long is the train ride from Casalnuovo di Napoli to Niscemi? Your journey takes about 11 hours on average.