Casarano to Comiso trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Casarano to Comiso. Trains leave from Lecce and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Casarano to Comiso train schedule: the first train leaves at 16:53, while the last ride is at 16:53. A Casarano to Comiso train cost about 173.7 €. But how long is the train ride from Casarano to Comiso? Your journey takes about 20 hours on average.