Cascina to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Frediano a Settimo and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Cascina to Messina train schedule: the first train leaves at 01:47, while the last ride is at 23:06. A Cascina to Messina train cost about 95.0 €. But how long is the train ride from Cascina to Messina? Your journey takes about 13 hours on average.