Cassino to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cassino and arrive at Alessandria every about 1 hour on average. If travelling with Trenitalia, you need to know the Cassino to Alessandria train schedule: the first train leaves at 03:38, while the last ride is at 21:17. A Cassino to Alessandria train cost about 56.2 €. But how long is the train ride from Cassino to Alessandria? Your journey takes about 8 hours on average.