Cassino to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cassino and arrive at Mazara del Vallo every about 6 hours on average. If travelling with Trenitalia, you need to know the Cassino to Mazara del Vallo train schedule: the first train leaves at 18:10, while the last ride is at 19:46. A Cassino to Mazara del Vallo train cost about 81.7 €. But how long is the train ride from Cassino to Mazara del Vallo? Your journey takes about 19 hours on average.