Catania to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Catania Acquicella and arrive at Alessandria every about 12 hours on average. If travelling with Trenitalia, you need to know the Catania to Alessandria train schedule: the first train leaves at 12:50, while the last ride is at 12:50. A Catania to Alessandria train cost about 85.05 €. But how long is the train ride from Catania to Alessandria? Your journey takes about 21 hours on average.