Cento to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Pietro in Casale, Salerno and arrive at Palermo Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Cento to Palermo train schedule: the first train leaves at 08:23, while the last ride is at 22:32. A Cento to Palermo train cost about 54.60 €. But how long is the train ride from Cento to Palermo? Your journey takes about 16 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Cento to Palermo and find low cost tickets starting from 15 €! When booking your train ticket a few weeks in advance though, you can find low cost trains from Cento to Palermo with fares starting from 13.90€, saving up to 57%.