Cesena to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cesena and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Cesena to Messina train schedule: the first train leaves at 08:24, while the last ride is at 22:16. A Cesena to Messina train cost about 109.85 €. But how long is the train ride from Cesena to Messina? Your journey takes about 13 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Cesena to Messina and find low cost tickets starting from 79 €!