Città di Castello to Alessandria trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 78 daily rides to get from Città di Castello to Alessandria. Trains leave from Firenze S. M. Novella,Rimini,Arezzo and arrive at Torino Porta Nuova,Milano Rogoredo,Milano Centrale,Alessandria every 10 minutes on average. The trip by train from Città di Castello to Alessandria last on average 02:08 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Città di Castello to Alessandria train schedule: the first train leaves at 00:40, while the last ride is at 22:28. A Città di Castello to Alessandria train cost about 9.90 €. But how long is the train ride from Città di Castello to Alessandria? Your journey takes about 4 hours on average. Trenitalia offers 22 direct trains between these two cities. If you need to travel this week, prices range from 18.25 € to 27.50€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Città di Castello to Alessandria with fares starting from 9.90€, saving 57% on average.