Città di Castello to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Arezzo and arrive at Ancona every 60 minutes on average. If travelling with Trenitalia, you need to know the Città di Castello to Ancona train schedule: the first train leaves at 06:05, while the last ride is at 17:13. A Città di Castello to Ancona train cost about 15.9 €. But how long is the train ride from Città di Castello to Ancona? Your journey takes about 5 hours on average.