Città di Castello to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Arezzo and arrive at Caltanissetta Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Città di Castello to Caltanissetta train schedule: the first train leaves at 19:02, while the last ride is at 19:02. A Città di Castello to Caltanissetta train cost about 164.0 €. But how long is the train ride from Città di Castello to Caltanissetta? Your journey takes about 17 hours on average.