Città di Castello to Caltanissetta trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Città di Castello to Caltanissetta. The first train to Caltanissetta leaves from Città di Castello at 19:02 and the last train departs at 19:02. If you choose a local train the trip lasts on average 16:33 hours. For your trip from Città di Castello to Caltanissetta by train you can choose to leave from one of Città di Castello main stations: Arezzo On Wanderio you can compare all schedules, fares and railway companies to Caltanissetta and book the best itinerary starting from Città di Castello.