Città di Castello to Catania trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Città di Castello to Catania. Trains leave from Arezzo and arrive at Catania Acquicella every about 2 hours on average. If travelling with Trenitalia, you need to know the Città di Castello to Catania train schedule: the first train leaves at 07:25, while the last ride is at 18:13. A Città di Castello to Catania train cost about 105.3 €. But how long is the train ride from Città di Castello to Catania? Your journey takes about 22 hours on average.