Città di Castello to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Arezzo and arrive at Enna every about 6 hours on average. If travelling with Trenitalia, you need to know the Città di Castello to Enna train schedule: the first train leaves at 04:25, while the last ride is at 04:25. A Città di Castello to Enna train cost about 126.35 €. But how long is the train ride from Città di Castello to Enna? Your journey takes about 16 hours on average.