Città di Castello to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 8 daily rides to get from Città di Castello to Messina. Trains leave from Arezzo,Salerno and arrive at Messina Centrale every about 2 hours on average. The trip by train from Città di Castello to Messina last on average 12:05 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Città di Castello to Messina train schedule: the first train leaves at 07:25, while the last ride is at 22:53. A Città di Castello to Messina train cost about 74.95 €. But how long is the train ride from Città di Castello to Messina? Your journey takes about 13 hours on average. Thanks to Trenitalia offers, you can save on your trip from Città di Castello to Messina and find prices starting from 49 €! If you need to travel this week, prices range from 45.50 € to 45.50€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Città di Castello to Messina with fares starting from 12.90€, saving 71% on average.