To get from Città di Castello to Messina by train you can catch one of the 8 trains that everyday travel between these two cities. The first train to Messina leaves from Città di Castello at 07:10 and the last train departs at 22:53. The trip by train from Città di Castello to Messina last on average 12:05 travelling with high-speed trains (Frecciarossa or Italotreno) If you choose a local train the trip lasts on average 05:06 hours. For your trip from Città di Castello to Messina by train you can choose to leave from one of Città di Castello main stations: Arezzo, Salerno Tickets price depend on the departure time and train type, the most economic train ticket available this week is from € 45 to € 45. Prices for next month range from € 19 to € 19. The most economic train is Intercity () that departs at 14:24 and arrives in Messina at 19:30 at € 19. On Wanderio you can compare all schedules, fares and railway companies to Messina and book the best itinerary starting from Città di Castello.