Colleferro to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Colleferro-Segni-Paliano and arrive at Comiso every about 3 hours on average. If travelling with Trenitalia, you need to know the Colleferro to Comiso train schedule: the first train leaves at 06:15, while the last ride is at 20:54. A Colleferro to Comiso train cost about 55.65 €. But how long is the train ride from Colleferro to Comiso? Your journey takes about 17 hours on average.