Comiso to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Comiso and arrive at Alpignano every about 4 hours on average. If travelling with Trenitalia, you need to know the Comiso to Alpignano train schedule: the first train leaves at 07:10, while the last ride is at 18:22. A Comiso to Alpignano train cost about 178.1 €. But how long is the train ride from Comiso to Alpignano? Your journey takes about 11 hours on average.