Comiso to Quattromiglia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Comiso and arrive at Castiglione Cosentino every about 6 hours on average. If travelling with Trenitalia, you need to know the Comiso to Quattromiglia train schedule: the first train leaves at 07:09, while the last ride is at 07:09. A Comiso to Quattromiglia train cost about 50.9 €. But how long is the train ride from Comiso to Quattromiglia? Your journey takes about 10 hours on average.