Como to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Como S. Giovanni and arrive at Caltanissetta Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Como to Caltanissetta train schedule: the first train leaves at 17:13, while the last ride is at 19:13. A Como to Caltanissetta train cost about 75.6 €. But how long is the train ride from Como to Caltanissetta? Your journey takes about 22 hours on average.