Como to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Como S. Giovanni and arrive at Caltanissetta Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Como to Caltanissetta train schedule: the first train leaves at 17:13, while the last ride is at 19:13. A Como to Caltanissetta train cost about 75.6 €. But how long is the train ride from Como to Caltanissetta? Your journey takes about 22 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Como to Caltanissetta and find low cost tickets starting from 73 €!